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Thus, angiogenesis may exacerbate inflammation in OA, by facilitating inflammatory cell infiltration [ 111].
Figure 3 allows for the possibility that unique genes encoded by these particular bacteria may influence the association, while Figure 4 provides data in support of the notion that P. copri thrives in an inflammatory environment, and may exacerbate inflammation.
An appealing hypothesis from an evolutionary and ecological perspective is that the P. copri-defined microbiota thrives in a pro-inflammatory environment and may exacerbate inflammation for its own benefit.
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PM-induced overactivity of the sympathetic nervous system may exacerbate inflammation-induced systemic insulin resistance [ 39].
This may maintain or exacerbate inflammation and widen the inflamed area [ 25].
Based on the existing data, we can conclude that galectin-4 may exacerbate intestinal inflammation in TCR mutational colitis model, while ameliorate intestinal inflammation in wild-type colitis model (Fig. 3).
Combined with increased expression of MMP-12, it may exacerbate valvular inflammation.
If chronic dietary fat intake may exacerbate airway inflammation during exercise, it may be important to consider modulating diet as a means to reduce the response to exercise, which may reduce asthma symptoms severity during exercise [ 46].
Mechanisms of VILI include alveolar overdistension (volutrauma), repetitive alveolar opening and closure (atelectrauma), oxygen toxicity, and biotrauma, the pulmonary and systemic response to alveolar overdistension that may exacerbate lung inflammation and contribute to multiple organ dysfunction [ 15, 16].
This loss of proliferative function results in the development of epithelium and renders the intestine permeable to luminal bacteria and antigens, which may exacerbate mucosal inflammation and dysfunction or cause bacteremia [ 2].
2-AG is also a substrate for COX-2 (Kozak et al., 2000), which metabolizes 2-AG into potentially harmful prostaglandins: a process that may exacerbate any inflammation and degeneration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com