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But in practice, I think it will ultimately be looked upon as a bad thing and may even directly backfire.
In more extreme situations like congenital DM with very large (CTG n expansions, where abnormal chromatin modification and defective bidirectional transcriptional control across the DM locus may directly couple to unbalanced DMPK production, the toxic effects of DMPK A may even directly contribute to special disease features [51], [52].
Previous experiments have indicated that cross-talk occurs between PPARα and LXRα, and it has been suggested that these two receptors may even directly interact.
Furthermore, results from animal studies have suggested that inhaled UFPs deposit more deeply into the lung and may even directly translocate into the circulatory system, thereby exerting adverse health effects via different pathophysiological pathways than larger particles.
With the idea of minimal intervention sets (MISs, [ 13, 14]) one may even directly search for those interventions that enforce a desired response (e.g. inactivation of a transcription factor).
Of key relevance here is the kinase-inducible domain (KID) in CREB and the transactivation domain in Myb, which share structural similarities implying that Myb and CREB may even directly compete for KIX domains in p300/CBP.
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From these reports and our data, it is reasonable to speculate that tau has direct involvement in lipid trafficking and may even bind directly to cholesterol.
In future British aid and foreign policies may even clash directly.
In the end, American troops opened fire only twice in six months, and one of those times a soldier shot himself in the foot.During the new Balikatan, Pentagon officials have hinted, American troops will be much more active, and may even get directly involved in combat operations.
The inhibition may even act directly on the protein and not on intermediate functionalities along the signalling pathways between the receptors of the stimuli and the protein.
You could argue that a rising tide lifts all boats; but you could just as easily argue that the interests of the ruling class do not strictly align with your own, and may even run directly counter to them.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com