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"By definition, they act without direct command and control from a wider network, and it is assumed that without such communications they may evade the 'tripwires' that would usually bring them to the attention of the authorities".
In addition, it would be possible to kill oncospheres as well as early cysticerci, which may evade the initial immune attack.
However, HCV may evade the IRF1 anti-HCV effect through core-mediated suppression of IRF1 synthesis.
This mechanism may evade the effect of multidrug resistance proteins, present in cancer cells [ 17, 18].
At more advanced stages of malignant transformation CSCs may evade the immune system, induce angiogenesis, and finally acquire metastatic capacities.
Thus, aberrant expression of B7-H1 has been postulated as a potential mechanism by which malignant tumors may evade the host immune response.
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Although this process is closely regulated under normal conditions, sometimes cells with deleterious genetic mutations may evade these checkpoints and replicate (rather than undergo apoptosis).
Once inside the macrophage the bacilli may evade or subvert the host immune response causing either a latent infection or active disease [2].
Researchers have hypothesized that B. dendrobatidis may evade or suppress the amphibian immune system (21, 22 ), but understanding of molecular and cellular mechanisms for such activity is lacking.
For the two sites, the virus may evade neutralization by one means completely different from the other, in part due to virus/Env fitness constraints.
This may reflect the non-distorting nature of the cross-links produced by this agent [ 5, 7] which may evade early detection by the cellular DNA repair machinery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com