However, the extent to which APA is coordinated between C. elegans tissues and how it may participate to establish cell identity has not yet been addressed.
Sampling tissue to establish cell cultures may vary slightly from other collection techniques.
Therefore, AMPK may establish and control cell polarity via the microtubule cytoskeleton.
The growth stimulus that ligand-activated erbB-2 and EGFR provides to lung adenocarcinoma cells may establish a background of continued cell proliferation over which other critical transforming events may occur.
Therefore, stem cells and differentiated cells may establish bidirectional communication during the reparative process [ 38].
CMV can also infect dendritic cells [ 33, 34] and endothelial cells, and may establish a latency reservoir in these cells too [ 30].
Identification of genetic and epigenetic differences between cancer progenitor cells and the bulk of other cancer cells may establish a causal link to their phenotypic differences.
Moreover, it may have important role to establish cell-mediated immunity by promoting the differentiation of Th1 cells from naive T cells and also to maintain that immunity [39].
The ongoing and parallel evolution of cancer cells may establish and maintain intratumor heterogeneity.
More recently, it was suggested that these two types of cells may establish a compound niche [ 9, 10].
