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One may envision a strategy in which SV breakpoints are approximately localized (e.g. by analysis of local alignments) and then precisely identified using AGE to align only subsequences that flank SVs.
Thus, one may envision a therapeutic intervention aimed at lowering caveolin-1 expression in lung cells for the treatment and/or prevention of the tissue damages that are caused by cigarette smoking.
Based on our findings that sinapinic acid possesses antiproliferative activity more effective than a well-known HDAC inhibitor sodium butyrate against HeLa and HT29 cells (Table 1), one may envision a role for sinapinic acid in a HDAC inhibitor-based cancer treatment.
The BRAF V600E mutation has been reported to enhance enzyme activity in vitro by a factor of about 500 [ 11]; thus, we may envision a poor drug response as well as a poor prognosis for tumors harboring the activating V600E mutation as well.
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They may envision an orderly election, built around a simple question: Do you like Clinton years better than Bush ones?
And while planners may envision an affordable New York City in college, in real life, the developers' political clout renders that dream all but quixotic.
In Excuse Me Ma'am, Benning's protagonists are often wearing bikinis or futuristic suits, ensembles a child may envision for a super hero.
Belichick may envision Tebow as a spare tight end or a multipositional contributor while counting on his credibility to convince Tebow it is his only way to stay in the N.F.L. Or maybe Belichick still winces at the memory of Brady's resembling a herniated cow on a scramble inside the Baltimore 10 in the final seconds of the first half of the A.F.C. championship game last January.
Hence, one may envision that for a small fraction of nucleosomes located at the promoter or enhancer regions of inducible genes, the signal-induced H3S10 phosphorylation facilitates chromatin remodeling for subsequent transcription initiation, whereas the global decline in H3S10ph may have distinct function in governing Brd4's release for subsequent P-TEFb recruitment and transcription elongation.
While some people may envision widespread illness from a dirty bomb, Dr. Brenner said the reality would probably be quite different.
One may envision that neurotransmitter receptor activation leads to a gradual build-up in the concentration of a given ion or second messenger molecule until some threshold level is reached.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com