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How PCN treatment may enhance innate anti-viral mechanisms is currently unknown but our data suggests that it likely involves B cell and/or CD4 T cell-dependent mechanisms.
By upregulating TLR4, chitin may enhance innate immunity against Gram negative pathogens and may, in concert with CXCL8-mediated neutrophil recruitment, boost neutrophilic innate host defence in bacterial skin infections.
Probiotics may enhance innate and adaptive immunity and have previously been demonstrated to augment the immune response to mucosally delivered vaccines (Fang et al., 2000).
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Therefore, GC-HIFU treatment may enhance the innate immune response.
However, other recent reports suggest that mTOR inhibition may enhance the innate immune response in DCs (Weichhart et al, 2008) and stimulate autophagy, which can enhance antigen presentation (Jagannath et al, 2009).
As the effects of aging on PMN bioenergetics may be amplified in conditions that increase pathogen burdens and may contribute to deficits in the initiation of adaptive responses, our study suggests a potential therapeutic strategy to enhance innate immunity [ 6].
Thus, boosting IL-15 activity could enhance innate and specific immunity and fight tumors.
Spirulina has also been shown to enhance innate and adaptive immunity.
Both IL-15 and IL-21 enhance innate and adaptive anti-HIV responses.
10.7554/eLife.03711.010 Figure 5. Statins enhance innate immune resistance to S. pneumoniae via NOS3.
They are designed to enhance innate or adaptive immunity depending on the antigen and vehicle.
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