Furthermore, our multiparameter analyses of the kinetics of taxol responses in cells with differential capacity to rapidly engage cell death may indicate new rationales for combining taxol with other anticancer agents.
Placental exosomes may engage in local cell-to-cell communication between the cell constituents of the placenta and contiguous maternal tissues and/or distal interactions, involving the release of placental exosomes into biological fluids and their transport to a remote site of action.
However, vesicular (intracellular) CB1Rs can still engage cell signalling (Gomes et al., 2009), which may be activated by lipophilic (membrane-permeant) cannabinoid ligands or via innate constitutive activity.
For cases where mAbs are intended to engage cell surface receptors and prevent receptor-ligand interactions (i.e., antagonists), it may be desirable to reduce or eliminate effector function for example to prevent target cell death or unwanted cytokine secretion.
Thus, by regulating the expression level of Pdro through their sterols levels, cells may engage a mechanism that regulates both LDL uptake and LE/LY dynamics, to ultimately control free cholesterol homeostasis.
In addition, in experiments involving lymphocytes, a stimulus is added to the culture medium in each well so cells may engage in division.
This may imply that tumor cells may engage in metabolic compensation in vivo to survive in periods of diminished glucose metabolism as suggested by decreases in FDG-PET signal during cancer therapy which do not necessarily correlate with good outcome [ 116].
Alternatively, cell surface receptors may engage the cleaved PA63, which exists as monomers or multimers in the blood of infected animals [9], [10].
A high-level expression of B7-H3 by transfection may engage TLT-2 to enhance T-cell responses.
The potential redundancy among LAZ1 homologs (At1g77220, 55% amino acid identity; At1g23070, 42% identity; Figure S4) may explain the weaker suppression of acd11 by laz1 compared to eds1, as EDS1 may engage other pathways to regulate or execute cell death.
