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Furthermore, while pre-treating cells with ATA failed to inhibit viral replication, pre-incubation of virus with ATA effectively reduced viral titers, suggesting that ATA may elicit its inhibitory effects by directly interacting with the virus.
Thus, TUG1 may elicit its biological activity through binding to PRC2, epigenetically regulating gene expression.
AG1801 may elicit its effect by providing a signal, rendering the cell resistant to the induction of apoptotic injury.
cGMP may elicit its cyto- protective effects via protein kinase G (PKG), which, in turn, activates mitochondrial protein kinase Cε via ERK signaling [ 33].
Mdm2 opposed Sp1 and pRb directed transactivation of the hTR promoter, suggesting a plausible mechanism whereby transfected pRb may elicit its effects by opposing the action of mdm2 (figure 3).
CYR61 (a member of the CNN family) has been shown to bind to integrin ανβ3 to mediate cell adhesion and migration (Kireeva et al., 1998) and CTGF may elicit its biological effects in a similar manner.
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Further studies revealed that ARC may also elicit its antiapoptotic function by other means.
Can we trust Syria, for instance, to report accurately what it may elicit in its torture chambers?
These in vivo observations indicated that EGF may elicit some of its actions by activation of nuclear ER.
McDougall's similar attitude toward the Civil War and its aftermath may elicit several gigabytes worth of academic controversy.
These results indicated that although structurally cytokines share the same signal transducing unit, its activation may elicit different effects, like different global phosphorylation level, activation of different STAT molecules what may influence the final biological activity.
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