Sentence examples for may dysregulate pathways from inspiring English sources

Abnormal expression levels in the cancer cell may dysregulate pathways, by inhibiting or stimulating them (Vogelstein and Kinzler 2004).

In spite of the complexities of interactions of multiple receptors and ligands in the BAFF system discussed above, future gene expression analyses of cells and tissues from rabbits with induced autoantibody production may reveal dysregulated pathways that permit autoantibody-producing B cells to survive.

We thus conclude that the dysregulated pathways may contribute to the X-ALD disease and VLCFA excess might act as a first causative factor of the cellular mechanism underlying X-ALD pathology.

Biological network models (hereafter referred to as networks) depict the inter-relationships between multiple signaling pathways and how their perturbations may dysregulate biological processes, eventually leading to the disease.

Taken together, functional classification of genes differentially expressed in HCC revealed dysregulated pathways which may contribute to the disease.

VP, acting through fluid-electrolyte mechanisms, may have a role in the mechanism of breast cancer initiation and progression, which may be prone to regulatory impacts through npcRNAs involved in the replication of dysregulating pathways of the mammary epithelium.

We call these pathways as dysregulated pathways and the candidate genes involved in the dysregulated pathways as dysregulated genes.

Compare our data with previously published datasets to ascertain dysregulated pathways and genes in osteoarthritis (OA).

Table 1 Involvement of sirtuins in the pathways contributing to premature aging when dysregulated Pathways contributing to premature aging SIRT1 SIRT2 SIRT3 SIRT4 SIRT5 SIRT6 SIRT7 Cellular/replicative senescence √ ?

We call such modules dysregulated pathways (DPs).

These four profiles are used to detect dysregulated pathways independently.