Sentence examples for may downregulate immune from inspiring English sources

Our preliminary data also suggest that successful antidepressant treatment may downregulate immune system activation.

That is, it may downregulate immune cells that normally are productively infected by the virus.

Moreover, it appears that while mycobacterial HSP70 stimulates an innate immune response, the situation with mammalian HSP70 is more variable and some members of this gene family may downregulate the immune response instead [ 34, 44, 54, 59].

Dasatinib has a dual effect in polymicrobial sepsis, where higher doses had deleterious effects but lower doses had beneficial effects, probably because lower doses may downregulate the immune response, avoiding extensive tissue damage.

It has been suggested that CD4+CD25+ cells downregulate immune responses acting via cell-cell contact or cytokine secretion [ 45].

Indeed, several membrane-bound or soluble factors produced by normal and neoplastic cells in the tumor microenvironment may downregulate the antitumor immune response and greatly influence the natural history of cancer.

Alternatively, immune activation may downregulate the production of androgens in low-quality individuals.

Therefore, it might be speculated that therapeutic strategies that aim to normalize the gut microflora in order to maintain proper gastrointestinal and immune system function may downregulate the abnormal inflammatory response and alleviate symptoms of RA.

One study suggests that CD69 may have a role in downregulating immune responses through TGF-γ [59].

These data indicated that HOTAIR may downregulate miR34a expression and promote gastric cancer cell metastasis.

For example, the realization that a molecule known as CTLA-4 plays a role in downregulating immune responses against tumours led to the development of a therapeutic human monoclonal antibody against CTLA-4.