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Furthermore, some mucoadhesive polymer-containing systems may directly change epithelial tight junctions and increase drug absorption and bioavailability.
First, modification of cis-acting elements and the recruitment of transcription factors may directly change patterns of gene expression (genes A and B in Figure 5).
The expression of splice forms was comparable in the stimulated cells, indicating that proinflammatory conditions may directly change the transcriptional profile of PTPN22 splice forms.
These data suggest that proinflammatory conditions, such as IFN γ stimulation, may directly change the transcriptional profile for PTPN22 splice forms and that PBMCs from healthy individuals are able to produce higher amounts of PTPN22-long forms.
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In addition, we found some pluripotent stem cell marker genes were slightly down regulated in hiPSC-ASPM cell clones (Fig. S3D) and iPSC grew normally (Fig. S3E), suggesting that Aspm mutations may not directly change the differentiation potentials in iPSCs.
Mechanical stirring may also directly change the size distribution of larger particles.
ROS may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered NO bioavailability or signaling [ 35].
While you can't directly change your student loan servicer, you may be able to change your student loan servicer when you consolidate or refinance student loans.
"When a situation can be directly changed, reappraisal may undermine the adaptive function of emotions in motivating action," the researchers write.
Experimental interference with the activity of sensory cortex may directly induce changes in the subject's behaviour or their perceptual report, and provides a tool with which to dissect the perceptual decision-making pathway.
This pattern change of co-expression at the transcriptional level may directly indicate the change of regulatory networks during different stages of cancer progression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com