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A key feature that may differentiate a cell's response to brca1 deficiency is how robustly it may react to increased DSB levels.
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Genetic mapping of the B genome in B. juncea has certainly indicated that a number of large-scale chromosomal rearrangements may differentiate the Brassica A and B genomes [ 22], although this study also indicated that at least three of the B genome chromosomes were virtually collinear with their A genome homoeologue [ 22].
The three sources could explain why CEC is not fully synchronized with CEP. 2) The CEPs are a kind of progenitor cell where one CEP may differentiate into a population of CECs, which would explain the earlier rise in the slope of the CECs as compared to the CEPs.
Near its opening the female canal may differentiate into a variety of tubular organs.
Human CD4+ T-cells may differentiate into a Th1 or Th17 phenotype.
Although macrophages and DC may differentiate from a common precursor, their capacities to process and present antigen differ significantly.
And because mesenchymal cells may differentiate into a variety of cell types in addition to cartilage, lead may also affect the development of other body systems.
Thus, lack of fully functional differentiation of retinal stem/progenitor cells in vitro does not predict how these cells may differentiate in a proper in vivo environment.
In fact pericytes may differentiate toward a variety of mesenchymal populations, such as osteoblasts, chondrocytes, adipocytes and fibroblasts [ 15], supporting the concept that adult multipotent MSCs are members of the pericyte family and reside in a specialized physical location known as the perivascular niche [ 16].
Interestingly, a recent publication suggests that following a transient period of c-Myc inactivation, at least some previously c-Myc activated suprabasal keratinocytes may differentiate to an extent sufficient to render them unable to re-enter the cell cycle after c-Myc reactivation [ 28].
A total cut-off score of 15 may differentiate depressive subjects; a score of 20 is usually required for inclusion into therapeutic trials [30]. 2.
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