Among the eligible 118 elementary and junior high school students followed for 1 year, 40 (33.9%) developed fatigue (fatigues score, 5.9 ± 1.4) and 78 (66.1%) did not develop fatigue (fatigue score, 1.1 ± 1.1).
However, these details are always subjected to repeated cyclic loads in practice, and fatigue cracks may develop and result in fatigue damage or failure.
The onset of type II failure may be insidious and may develop when respiratory muscle fatigue complicates preexisting disorders, such as pneumonia or status asthmaticus, which present initially with hypoxemia without hypoventilation.
These results are in accord with those of Brown & Hasser [11] who also found reduced fatiguability in aged EDL rodent muscle, and with human studies which show that peripheral fatigue may develop more slowly in the elderly [46] [47].
However, due to high service load, harsh operating conditions or fatigue, faults may develop in gears [1].
Patients may develop insomnia, weight loss, chronic fatigue, and an inability to perform daily activities.
In addition, Q fever fatigue syndrome may develop in ≈20% of those infected (17 ), which is generally incompatible with a military career and has substantial effects on patients' quality of life.
Our finding that 65% of acute C. burnetii infections were asymptomatic is consistent with previous reports (17, 18 ), but even in asymptomatic persons infected with this pathogen, long-term complications such as chronic Q fever and Q fever fatigue syndrome may develop.
Patients may develop burdensome symptoms like pain, dyspnoea, fatigue and cough and they may undergo radical treatment, including surgery, chemo- and radiotherapy.
