Telangiectasia and atrophy may develop rarely.
Furthermore, our finding of significantly impaired verbal learning in non-demented PD fits with recent data showing that encoding deficits and hippocampal atrophy may develop early in the disease [ 12, 14- 18].
In advanced stages of DFO retinopathy, frank RPE and photoreceptors atrophy may develop in the macula, as well as migration of hyperreflective subretinal deposits towards the outer plexiform layer interrupting the overlying external limiting membrane [ 32].
51 The most important limitation of vPDT is long-term chorioretinal atrophy which may develop in some patients, contributing to vision loss.
Hypoechoic regions may develop as a result of degeneration or atrophy.
However, recent work indicates that encoding deficits [ 12- 14] and even hippocampal atrophy [ 15- 18] may develop in non-demented PD, independent of verbal retrieval.
However, more than half of these patients, particularly those who receive either delayed or inadequate treatment, may develop chronic disease with consequent poor visual prognosis due to cataract, glaucoma, subretinal fibrosis, choroidal neovascularization, or choroidal atrophy [2].
Neuroendocrine alterations in HD may develop over time in relation to the phenotype, as a result of advanced neuronal degeneration (e.g., causing atrophy of the pituitary gland) and progression of the disease.
"Alternate identities may develop instead".
