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Additionally, the available CT component with high-resolution capabilities can provide additional diagnostic clarity of the metabolically active pathology and may detect additional, non-active pathologies.
It has also been reported that a more sensitive technology may detect additional mutations that confer resistance to anti-EGFR therapies [ 24].
TLRs may detect additional microbial structures in a CD14-independent manner, including the following: flagellin (TLR5); prokaryotic unmethylated CpG motifs in bacterial DNA (TLR9); mycobacterial lipoarabinomannan (TLR2); fungal constituents (TLR6 and TLR2 heterodimers); and even double-stranded viral RNA (TLR3).
Although HLAGA7 provides a robust sex-linked marker for use as a screening tool in hop breeding programs, further research may detect additional polymorphic loci located on autosomes which affect gender in a broader range of genetic material.
PET may help to support or negate the suspicion for malignancy in areas of CT abnormality (Fig. 5), may detect additional, previously unsuspected sites of disease, and may assist in locating the easiest site to biopsy, in order to prove recurrence of cancer.
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This was not achieved for A. hyacinthus (Figure 3D), however, suggesting further sampling of this species may potentially detect additional rare ribotypes.
Strategies that combine several phenotypes in an mGWAS may potentially detect additional genetic loci and further their functional characterization.
We hypothesized that a volumetric assessment of MET-PET data may help to detect additional subareas of active tumour volume, over and above the information provided by Gd-DTPA enhancement alone.
In addition, IGRA may detect one additional case of LTBI out of 56 patients that would otherwise be missed using solely TST.
As increasingly deep annotation of the human genome accumulates, it may be possible to detect additional associations between lentiviral integration and particular bound proteins, potentially allowing identification of host cell factors operating in the absence of LEDGF/p75.
It should be considered, however, that the duration of controlled clinical trials is usually 4 5 years, and this may be insufficient to detect additional benefit of some drug classes, especially in low-risk patients.
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