In summary, the current studies were intended to provide a rational to test lapatinib as a single agent or in combination with chemotherapy in patients with high-risk primary or metastatic endometrial cancer and to identify candidate markers that may help define subsets of patients most likely to benefit from treatment with lapatinib.
The current studies were intended to provide a rationale to test dasatinib as a single agent or in combination with chemotherapy in patients with ovarian cancer and to identify molecular markers that may help define subsets of ovarian cancer patients most likely to benefit from treatment with dasatinib.
These studies may help to define subsets of patients who may have more or less benefit from an anti-reflux operation or who may be more or less disposed to have complications.
The presence of specific CBPs in distinct neuronal populations has prompted the suggestion that CBPs may define specific subsets of interneurones (Antal et al. 1991).
Baseline levels of these five serum factors compose a risk signature that may define the subset of patients most likely to benefit from bevacizumab-based therapy in terms of response rate and survival times.
Our study explores early TS as a prognostic tool in mRCC and shows that the depth of remission may define a subset of patients with superb response to VEGF-targeted therapies, at least in mRCC.
Several researchers have claimed that classification of tumours on the basis of HER-2/ neu overexpression or amplification may define a subset of breast cancer in which the net effect of a risk factor could be rather more obvious and its impact on breast cancer development more clear.
In order to explain this incompatibility, several researchers have claimed that classification of tumours on the basis of HER-2/ neu overexpression or amplification may define a subset of breast cancer in which the net effect of a risk factor could be rather more obvious and its impact on breast cancer development more clear [ 3, 7, 8].
These heterogeneous AISs, in terms of localization and Nav channel composition, may thus confer different excitability properties and contribute to define subsets of MNs with different firing properties [ 49].
Similarly, for each, we may define a connected subset,, in satisfying (1) ; (2) joins with infinity in, . ; joins with infinity in, and the superior limit of contains a component joining with infinity in.
