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They may define sites of protein interaction with DNA or other proteins, based on ontology analysis.
However, as PET images include a greater body area, it may define sites of disease outside the scope of that seen on routine CT scanning.
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The two continuous water densities are separated by the residues Ser63 and Glu90, which are highly conserved among the ChRs, and may define constriction sites as discussed previously.
For comparative purposes, we also apply current methods used in the literature and show how these may fail to define site-specific losses.
On the other hand, MAEL-specific residues and its potential active site may define another nuclease activity.
In addition to utility in gene discovery and the study of differential expression, sequenced cDNAs (in the form of ESTs) allow for the elucidation of gene structure; specifically, alignment of ESTs to corresponding genomic loci identifies introns within the genome sequence and may define transcriptional start and stop sites.
The abnormal molecular phenotypes of these mutations comprise: (a) complete exon skipping, (b) reduced efficiency of splicing, (c) failure to remove introns (also termed intron retention or intron inclusion), or (d) cryptic splice site activation, which may define abnormal exon boundaries in transcripts using non-constitutive, proximate sequences, extending or truncating the exon.
The exploratory analyses also suggested that site characteristics may impact outcomes and this also should be an area for future research in order to more clearly define site characteristics that help rather than hinder women in coping with COS.
In summary, Ysp2p and its homologs are ER proteins strongly enriched at puncta in the cER that may define a sub-class of ER-PM contact site.
This technique is very useful in the detection of stones and in the creation of virtual cholangiographic pictures and may be very valuable in defining sites of leaks as it has the functional dimension that conventional MRCP does not.
Because eschar is a site for rickettsial introduction, the pattern of rickettsial gene expression observed here may define how rickettsiae counteract the host defense.
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