Polyamines bind to nucleic acids and proteins, decrease membrane permeability, may help cells survive abiotic stresses [ 20, 21]; polyamines may also act as nitrogen stores.
Polyamines bind to nucleic acids and proteins, decrease membrane permeability, may help cells survive abiotic stresses {Igarashi, 2006 #2726} {Groppa, 2008 #2724}; polyamines may also act as nitrogen stores.
The effect of the hypokalaemic periodic paralysis mutations on S4 translocation may be their predominant effect to decrease membrane excitability in channels that have fast inactivated in the process of firing action potentials.
As a result, this may reduce the compression in the OHC and decrease membrane tension to shift the Vpk of NLC negatively (Fig. 6).
KATP channels expressed on cardiomyocytes are thought to decrease membrane excitability when activated through stress and thus may be key mediators of ischemic tolerance [ 46].
Because neurotransmitter release is dependent on calcium influx, a disturbance in the concentration gradient of calcium across the cell membrane may decrease the influx of calcium ions into the cell and impair neurotransmitter release [ 65].
These results, along with downregulation of all the genes of lipoproteins of S. aureus in group IV and V, suggest that OPP exposure may decrease stability of the staphylococcal membrane.
The membrane theory of aging proposes that life span is inversely related to the level of unsaturation of membrane phospholipids [ 2, 3], and it has been hypothesized that CR may retard aging by decreasing membrane fatty acid unsaturation [ 2, 4].
For scaling up this process, the membrane fouling by the adsorption and infiltration of cells and macromolecules is the main concern, which may lead to the decreased membrane flux and selectivity.
Because activation of Kir2.3 channels causes membrane hyperpolarization [36], PREGS may decrease excitability of neurons and glial cells in these regions.
