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Conversely, CYP3A4 inducers like rifampicin, phenytoin, carbamazepine, and St John's Wort may decrease levels.
If cocaine induces CYP3A4 in humans as well, it may decrease levels and effectiveness of the many ARVs that are CYP3A4 substrates, including most NNRTIs and PIs.
Reducing antibiotic prescribing in primary care may decrease levels of antibiotic resistance nationally and internationally, but it may also have substantial effects locally.
12 Short-term prophylaxis should also be considered before administration of intravenous radiologic contrast, streptokinase, or tissue plasminogen activators, because previous studies have suggested that these agents may decrease levels of CI-INH in these patients.
Another possibility is that hypothyroid patients are treated with levothyroxine, which is known to somewhat reverse cardiovascular risk factors (for example, thyromimetic drugs may decrease levels of atherogenic lipoproteins).
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However, statins may also decrease levels of CoQ10, an essential component of the respiratory chain, leading to mitochondrial dysfunction [ 13].
These data suggest that increased levels of miR-18a in men may subsequently decrease levels of ERα, thus blocking the documented protective effect of estrogen and stimulating HCC pathogenesis.
Our study offers evidence that BI-2536 mactactoto decrease levels of mutant p53 while not affecting wild type p53.
Gene technology - like traditional breeding- may increase or decrease levels of naturally occurring proteins, toxins or other harmful compounds in foods.
Beyond a reduction in adiposity, changes in other modifiable factors, including weight control, or use of NSAIDs, may help to decrease levels of acute-phase inflammatory proteins.
Some authors have previously suggested that high doses of NAC may increase MDA levels, whereas lower doses may decrease MDA levels [46].
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