For example, although our findings reflect CRC risk in extensive UC patients, a significant proportion of patients will have left-sided disease or proctitis only in general populations that may decrease the estimate of overall CRC risk.
Instead, we commented on factors that might decrease the validity of estimates, recognizing that small sample size, while it may decrease precision of estimates, is not in itself a source of bias.
While this sampling allocation method may decrease the accuracy of estimates on the global level, it will increase our estimates for specific domains particularly the early years when number of trials was scarce.
Preliminary testimonies by NY wheat producers indicate average yields so far in 2014 as of July 24th so final yield estimates may decrease a bit.
However, additional factors may decrease annual energy production estimates to varying degrees, including loss of energy because of distance of transmission, as well as availability (that is, how reliably the turbine will produce power when the wind is blowing).
This may indeed be an early estimate of the median survival for this cohort and, as more data for this cohort becomes available, this median estimate may decrease over time like that observed with the K-M estimator (Additional File 1).
In comparison, our model predicts that a similar reduction in TV advertising exposure may decrease consumption by about 3 8%, an estimate that remains under the ceiling implied by the Epstein study.
Further work is needed to determine the optimal recording timeframe for diary recordings, as adherence rates may decrease over time, thus reducing the validity of estimates.
Despite the lack of a significant improvement in fit, the parameter estimates suggest that the polygenic variance may decrease with age.
Furthermore, the generation interval may decrease during the course of the outbreak because of quicker interventions, leading to possible bias in the estimates of R (2 ).
