Ultimate outcomes are a combined result of changes in intermediate outcomes over time and may include decreased asthma morbidity and mortality, incidence of asthma, emergency department utilization, decrease in hospitalization rates, use of rescue medicines, activity limitations among persons with asthma, and decrease in number of school or work days missed by persons because of asthma.
Alternatively, it has been suggested that SCIT may decrease the risk of future asthma and improve asthma symptoms and medication usage, which obviously would provide substantial benefits to SCIT not captured in this analysis.
14 Bronchial hyper-responsiveness, raised exhaled nitric oxide and reduced lung function have been observed in children with AR. 15 Pharmacotherapy for AR improves asthma control; 16 17 allergen-specific immunotherapy (SIT) for rhinitis may decrease the progression of rhinitis to asthma.
Thus, Notch signaling plays a key role in maintenance of healthy epithelial barrier integrity and may decrease the risk of AD-associated MPD or asthma development.
This finding supports the hygiene hypothesis, a theory that exposure to infectious agents early in life may decrease the risk for allergic diseases such as asthma later in life.
These findings provide compelling evidence that reductions in emissions from the sources that give rise to these pollutant levels may decrease the associated direct health care costs of asthma in this region.
Reducing asthma symptoms with therapy for AR could potentially decrease asthma-related health care resource utilization.
However in pregnant women with asthma, peak flow rate, FEV1 and FVC may decrease particularly during acute exacerbations [ 43].
The limited available evidence suggests that tachykinin receptors antagonists may decrease airway responsiveness and improve lung function in patients with asthma.
Maternal α-linolenic acid, total n-3 essential fatty acid, and palmitic acid intake may decrease, while arachidonic acid intake may increase the risk of asthma in the offspring [ 47].
