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It is believed that, during this internalisation process, β-catenin may decouple from the cadherin complex and translocate into the nucleus to initiate canonical Wnt signalling.
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Almost exclusively, the previous studies have focused on a single-degree-of-freedom system, with the understanding that for any linear dynamical system, one may decouple a specific mode of interest from other degrees-of-freedom.
One of the few agents we do know of in booze besides ethanol that may exacerbate some of its risks may be decoupled from price as well.
Molecular change may be decoupled from phenotypic change in the sense that many changes in germline DNA may lead to vanishingly small changes in phenotype [ 18, 28], but mammalian molecular evolution is nevertheless a part of life history evolution, and the treatment of germline mutation rates as a component of life history deserves further attention.
Although emerging economies may have decoupled from America, their monetary policies have not.
We hypothesize that both inactive and active states of Smo may be decoupled from Ptch1-mediated inhibition of ciliary trafficking and Smo activation on the cilium thus requires additional steps.
Genus diversity may be decoupled from species diversity if species richness is unevenly distributed among genera.
Finally, in some situations, the macrocirculation may be decoupled from the microcirculation [ 10, 11], thereby reducing the effectiveness of haemodynamic optimisation based only on commonly measured macrocirculatory parameters and complicating the haemodynamic management of critically ill patients.
This result is not unexpected given the long period from exposure to blood collection in this study, and evidence that current organochlorine serum concentrations may be decoupled from exposure levels due to intakes from food sources [ 43] and differing metabolism and degree of organochlorine storage in individuals [ 44].
The rate of fixation of weakly selected mutations may be decoupled from Ne by genetic draft (Gillespie 2001); however, draft should also depend on the local recombination rate, and we see no difference between regions of high and low recombination in our patterns (supplementary fig. S1, Supplementary Material online).
In other words, the leachate composition from a tephra deposit subsample is the partial product of processes which are independent of those governing gas-tephra interactions, and hence, the leachate compositions may be variably decoupled from gas-tephra interaction processes.
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