Sentence examples for may decisively contribute from inspiring English sources

73 Many lines of evidence indicate that the components of the PI3K pathway may decisively contribute to the resistant phenotype, and therefore it is a major target for anticancer drug development.

Because the brain damage observed in BM, including hippocampal apoptosis, is mainly due to the host inflammatory reaction [ 37], a down-modulated immune reaction may decisively contribute to diminished hippocampal apoptosis observed in vitamin B6-treated rats.

We believe that cloud-assisted architecture can decisively contribute to event monitoring performance improvement.

Firms' strategic movements can decisively contribute to the definition of the DD.

This can decisively contribute to not unnecessarily putting efforts in approaches which are subsequently rejected by the competent authorities.

Furthermore, the local tumour microenvironment has been shown to decisively contribute to cancer growth, metastasis, and progression to resistance (Bissell et al. 2002; Wiseman and Werb 2002).

Further investigation of relevant laminin epitopes in pathogenic autoimmunity would facilitate the development of appropriate diagnostic tools for thorough characterization of patients' antibody specificities and should decisively contribute to designing more specific therapeutic interventions.

There is a suggestion that high concentrations of GSH, GSH-Px and GSTpi, independent of other intracellular alterations, do not decisively contribute to MDR [ 19, 20].

In recent years, it has been reported that components of PI3K/AKT and MEK/ERK signaling pathways are frequently altered in human tumors, which decisively contribute to the clinic drug resistance.

Awareness of time in its three categories of past, present, and future has decisively contributed to man's success in the struggle for existence.

Instead, targeted phosphoproteomics would allow monitoring hundreds of phosphosites involved in particular pathways, thus decisively contributing to unambiguously identify defects causing the onset of the signaling pathologies.