Sentence examples for may critically contribute from inspiring English sources
Therefore, MLP dowregulation occurring during gene reprogramming may critically contribute to mechanical failure of the myocardium.
The downregulation of genes involved in Wnt signaling observed here may critically contribute to the decreased number of ISCs observed in Ap4-deficient mice, because the Wnt pathway has been implicated in the maintenance of stemness and suppression of differentiation in ISCs43,44,45.
IEC are crucial for maintaining intestinal homeostasis [18] and failure to control inflammatory processes at the epithelial cell level may critically contribute to the disease pathogenesis.
These observations indicate that the level and availability of CXCL12 for CXCR4 is tightly regulated under normal conditions and the present data indicate that CXCR7, which is widely expressed, may critically contribute to this regulation.
This mechanism may critically contribute to the robustness of gene expression dynamics governing proper developmental control.
We have thus identified NRP-1 as an essential co-receptor for PDGFR signalling, which may critically contribute to the formation of blood vessels and other mesenchymal tissues.
Low levels of autophagy may also critically contribute to the selective survival and growth of UV-irradiated melanoma-cell escapers.
Sensitisation and activation of mast cells involving local IgE may therefore critically contribute to disease pathogenesis.
AP4 achieves this effect by direct repression of p16 and p21, and may thereby critically contribute to c-MYC function and tumor progression.
Ancestral membrane-spanning receptors related to those genes which appeared to transform the proto-synaptic scaffold to a functional synaptic machine were present in neoproterozoic animals, possibly lost in the sponge, and may have critically contributed to the evolution of the post-synaptic complex in a Poriferan-Eumetazoan common ancestor.
These data indicate that profilin-1 might critically contribute to atherogenesis and may represent a novel therapeutic target.
