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Exact(6)
Therefore, fluid overload leading to IAH and renal dysfunction may counteract its own resolution.
Herein we hypothesize that blocking endogenous IP-10 activity after CVB3 infection may counteract its chemotactic activity and compromise the excessive pathological injury in the heart tissue mediated by viral induced Th1 immune responses.
Thus, prevention of ARpolyQ misfolding and nuclear translocation may counteract its neurotoxicity (see below).
Whether lowering the fever burden is warranted in all instances or unrecognized side effects may counteract its benefit is so far unknown.
In many food products, the presence of acetaldehyde seems to be associated with other protective components which may counteract its detrimental effects.
Despite its outstanding preclinical antitumor activity, rapamycin has been shown to increase Akt phosphorylation, which may counteract its anticancer efficacy [ 14, 15] And could be a reason why mTOR inhibitors only exhibit modest antitumor activity in patients.
Similar(54)
A wide range of side effects may negate and counteract its positive initial effect; this implies side effects of hypothermia per se and side effects of rewarming or inconstant maintenance of temperature levels [ 13- 17].
It has been suggested that high levels of MDM4 may counteract Nutlin because its binding to p53 is not inhibited by the treatment [ 15, 16, 44], although the hypothesis is still controversial [ 45].
It is assumed that the mercury content of fish may counteract the beneficial effects of its n − 3 fatty acids.
Indeed inhibiting the activity of DYRK1A may counteract the phenotypic effects of its overexpression.
However, it is important to note that a compensatory anti-inflammatory activity of IL-10 may counteract APN and hence block its bioactivity.
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