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And in the Discussion they don't discuss whether or not a different set of salt bridge switches may coordinate conformational changes.
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Thus, kinking of the bridge helix at HN and HC may allow it to coordinate conformational coupling between the two sides of the polymerase cleft in ways that remain to be elucidated.
Pheromones may coordinate reproductive timing for females coming into estrus.
Alternatively, these Chls may coordinate with peptide carbonyl groups.
Firstly, clustered miRNAs may coordinate to regulate the PPI network.
We speculate that such intra-protein forces may also be a critical factor in driving coordinated conformational changes between distant domains in many other systems, which are presently not fully characterized mechanistically (Cui and Karplus, 2008; Changeux and Edelstein, 2005).
P-gp couples drug efflux with ATP hydrolysis by coordinating conformational changes in the drug binding sites with the hydrolysis of ATP and release of ADP.
They may actually coordinate protein signals for proper fetal development.
We propose a general framework for approximating the potential of mean force (PMF) along a reaction coordinate in conformational space.
EP bridges may enable coordinated cell coalescence, signaling, and migration.
These referrals may be coordinated through a centralized coordinating system.
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