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These results suggest that our analyses are consistent with the previous reports [ 3, 27, 28], and it is conceivable that these domains may cooperate and thereby confer particular functions on the proteins containing them [ 9].
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Co-occupied sites showed enrichment not only in E and M-boxes for MITF, but also in motifs for SOX10, CREB, and ETS1, TFs that may cooperate with MITF and BRG1 to regulate associated target genes.
These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation.
These results suggest that COPT2, COPT3, and COPT4 may cooperate with COPT6, respectively, and COPT7 acts alone for Cu transport in different rice tissues.
Together, these data further supports the idea that Spt16p may cooperate with Sir1p and function in regulating the binding of Sir2 4p binding to heterochromatic region.
Though VW and Volvo may cooperate on engineering and technology, there's no enthusiasm at headquarters in Gteborg, Sweden for a takeover offer from Piech or anyone else.
Though VW and Volvo may cooperate on engineering and technology, there's no enthusiasm at headquarters in Gteborg, Sweden, for a takeover offer from Pich or anyone else.
Thus, TGF-β and FGF-2 may cooperate with each other and may regulate EMT of various kinds of cells in cancer microenvironment during cancer progression.
During early development, the preoptic area is under the influence of both types of signals, Fgf8 (produced at the anterior neural ridge; Ye et al. 1998) and Shh, and may cooperate for the production of dopaminergic neurons from this progenitor domain.
Moreover, AR is known to promote mTOR activity (Xu et al. 2006 b ), thus suggesting that combining mTOR- and AR-directed therapeutics may cooperate to improve cellular and clinical responses to therapy.
Of special interest, transcription factors such as NF κB and STAT3 may cooperate to promote the development and progression of cancer, by controlling the expression of antiapoptotic and proliferative genes, in addition to intervening in the regulation of angiogenesis and invasion [ 1, 8, 10].
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