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The expression of Shh in ureteric cells suggests that it may control renal development via direct effects in the ureteric cell lineage.
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Our results suggest that both spontaneous and urethane-induced renal tumors are controlled by the same genetic locus, i.e., Rtm1, although we cannot exclude that additional loci may control spontaneous renal tumor susceptibility in AIR mice.
Renal tissue of LN patients shows increased release of nuclear HMGB1 compared to control renal tissue.
Mechanisms by which inhibition of mTOR may control tumour growth in patients with renal cancer remain unclear.
Accept change, and we may control it".
Intragenic L1s may control hundreds of genes.
This mechanism may control Rasgrf1 imprinting.
Morphogen sonic hedgehog (Shh) controls renal patterning [102, 103].
No staining was detected in control renal tissues).
Hence PGP may influence renal function via the control of intracellular concentration of a known toxin in the tubular epithelial cells.
However, the mechanisms by which these antihyperglycaemic drugs may improve renal outcome beyond glycaemic control are unclear, but may involve improvements in body weight, blood pressure, renal haemodynamics and albuminuria or lipid profiles.
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