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The receptor may control calcium influx through the outer cell membrane, thereby altering the concentration of free calcium ions within the cell, or it may control the catalytic activity of one or more membrane-bound enzymes.
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Further, PP2Cα functions in mammalian neurons to control calcium flux (Li et al. 2005), suggesting that PP2C phosphatases may have undiscovered roles in neuronal development.
"So then you look for proteins that help control calcium.
The protein tightly binds calcium carbonate crystals and may control their formation preventing clogging of the ducts [16] [19].
It has been suggested that small-conductance calcium-activated potassium (KCNN/SK/KCa2) channels may control membrane excitability through attenuated NMDA receptor activity.
Microtubules may control the activity of plasma membrane ion channels such as those that transport calcium, and lipid signaling may be involved in this process.
The observed magnitude of the rise in sarcoplasmic calcium varies between slow and fast muscle types, which suggests it may control the contractile characteristics of muscle fibres [ 2].
The role of CALM2 in cancer is less well understood but may be linked to cancer since it is involved in controlling calcium signaling [ 61, 62].
These alterations may be due to direct or indirect effects of nitric oxide interacting with the mechanisms controlling calcium levels in platelets and in other tissues.
We hypothesize that in other organ systems where Pax6 and calcium signaling are both known to be required, such as axon guidance [ 69, 70], Pax6 dosage may directly control the kinetics of the calcium response of cells to their external environment.
This model represents intracellular calcium dynamics by including the subspace calcium dynamics that control L-type calcium channel current (ICaL) and calcium-induced calcium release (CICR).
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