The operon may contain a regulator gene, but this can also be situated elsewhere in the genome.
Further, U.P.S. units contain regulators, which create more stable electric power for sensitive equipment.
Pericentromeres are involved in the cohesion of sister chromatids during cell division [ 43], subtelomeres maintain chromosome stability [ 24, 44] and gene deserts do not have a well defined function but they may contain long-range regulators of gene function [ 45, 46] or structural regions such as the nuclear matrix attachment sites [ 47, 48].
The results further suggested that NcrA, NcrB, or NcrC may contain a transcriptional regulator.
HIF-1 transactivates and down-regulates ERα [ 45, 46], so the co-regulator(s) may contain proteasome activity.
We note that all constructed hypothesis networks are completely consistent with respect to their direction of edge effects, and may contain loops only if a regulator node appears as a dataset molecule in D at the same time.
Since ubiquitination by proteins such as carboxyl terminus of Hsc 70 interacting protein, a regulatory subunit of 26 S proteasome SUG1/TRIP1 and E6-AP ubiquitin ligase promotes ligand-induced degradation of ERβ [ 32], ERβ-ARNT co-regulator complexes may contain proteins inducing ARNT degradation.
Our data show that Pri peptides control selectivity of Ubr3 binding, which suggests that the family of sORF peptides may contain an extended repertoire of protein regulators.
Hence, this list of genes may contain novel information about potential unidentified regulators of cellular aging, probably including genes that are relevant for cellular aging in vivo.
Finally, the apicomplexans P. faliciparum and T. gondii lack HKs, although Cryptosporidium parvum may contain one HK-like protein although response regulator and PAS domains are absent.
