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Ecosystems may contain functional redundancy whenever species are capable of replacing each other [ 11- 13, 91].
VISTA comparison of human and mouse sequences reveals several sites of conserved non-coding sequences; these may contain functional elements necessary for proper expression.
One potential explanation is that exon1, exon2 and exon3 may contain functional elements that are shared by other ncRNAs and/or distributed more widely.
Large regions of gene amplification in cancer cells can be detected by techniques such as comparative genomic hybridization and high-density arrays, which helps to localize areas that may contain functional oncogenes.
We therefore removed the MegaBLAST hits with ≥30% identity and ≥30 bp in length from primate-shared and rodent-shared HCNSs since the sequences with ≥40% identity may contain functional elements (McGaughey et al. 2008).
Regions 1 and 11 can be considered novel and may contain functional variants contributing to the genetic control of bovine stature, because they harbor DUSP23 (BTA-3: 10.02-10.03 Mb) and POLR2A (BTA-19: 27.78-27.80) as candidate genes, respectively (Lanktree et al. 2011).
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Indeed, alternative splicing could produce different isoforms which may or may not contain functional binding sites, playing an important role in modulating the interaction between miRNA and target.
Four out of five of these basic amino acids are identical in TcNPR1, suggesting that TcNPR1 may also contain functional nuclear localization sequences.
This loop may contain a functional motif that contributes to the functional specificity of LGI1.
Latest database may contain new functional genes which were not yet assigned functional information when the analyzed genome was sequenced.
Thus the transgenic transcript may contain a functional virus replication site.
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