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The public map also bears a disclaimer that the map may contain erroneous reports.
In NGS experiments, shorter reads obtained may contain erroneous data like poor quality reads, adapter sequences, base calling errors and some insertions/deletions among the original reads.
Due to biases in sequencing technology, exome data sets may contain erroneous k-mers that occur 10 or more times, particularly for regions that contain very deep coverage (which can exceed 1000-fold for some exonic targets).
Furthermore, since we used sub-cellular localization information to eliminate potential false positive protein associations, this information, too, is to some degree based on predictions alone and may contain erroneous assignments.
Considering that some of sequenced reads may contain erroneous bases, we design an error-tolerant mapping algorithm shown in Figure 2. We search for sub-sequences of paired reads which are indexed as mtDNA fragments and the accuracy of mapping is determined by the pairing distances.
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Analyses were later expanded to total promoters, most of which lack defined TSSs and may contain more erroneous gene models due in part to less EST support.
Of the 688 gene triplets, only 294 (43%) do not contain erroneous sequences and may correspond to true events, while a total of 394 (57%) are putative artifacts.
Structure activity relationships collected from medicinal literature and stored in bioactivity databases may contain noise or erroneous reported activity measurements, due to human error or experimental uncertainty, that could potentially affect the performance of data-mining techniques [40 43].
As an erroneous roof topology graph may contain several errors, a heuristic search is applied to find the optimum sequence of graph edits to correct the errors one by one.
Another reason that is given for the weak acceptance of automated reasoning by the mathematical community is that the programs are not to be trusted since they may contain bugs—software defects—and hence may produce erroneous results.
We propose that uncharacterized parts of protein sequences should also be considered "dark matter", because they match its definition: they may contain novel domains, undetected domains, non-globular linkers or erroneous sequences.
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