Sentence examples for may constitute early from inspiring English sources

Of particular relevance to the study we present here, analysis of blood and urine of rats fed a diet supplemented with Roundup-tolerant NK603 GM corn for 90 days showed statistically significant differences in multiple components [29], which has been suggested may constitute early signs of liver and kidney toxicity [30].

These findings suggest that ASXL1 mutation may constitute an early hit in the pathogenesis of MDS.

Thus, endothelial dysfunction may constitute an early predictor and independent contributor to sepsis-associated MODS and mortality in aged mice.

These data suggest that an enhanced expression of the mature MIC-1/GDF-15 formayay constitute an early transforming event during prostate carcinogenesis.

AGAs are generally considered to be rare autoantibodies; however, Bizzaro and coworkers [ 21] suggested that the presence of AGAs in high titer in the absence of a clear clinical manifestation may constitute an early sign of systemic autoimmune diseases.

Furthermore, quantification of BBB permeability may constitute an early prognostic factor in the pathogenesis of multiple sclerosis, while MRI features such as multiple sclerosis plaques, loss of N-acetyl-aspartate, decrease of magnetic transfer ratio (MTR), changes in T1, and tissue atrophy may be considered as consequences of a longer lasting neuroinflammation.

With IL-8 being currently demonstrated as the single most up-regulated gene in surgically resected GC tumors, the up-regulation of this gene throughout gastric cancer progression may constitute an early and important event in the disease, initiated and maintained by H. pylori infection.

These observations are consistent with the notion that SCF-R+ cells may constitute an early proliferative LC precursor pool that can quickly differentiate into SCF-R− cells with maintained LC differentiation ability but reduced proliferation capacity, resulting in an ultimate loss of differentiation capacity over time.

Gupta's proposal is also supported by other work investigating protein structural relationships and studies that suggest that Gram-positive bacteria may constitute the earliest branching lineages within the prokaryotes.

These changes in protein and lipid components of BAL following asbestos exposure constitute early indices of lung inflammatory reactions which may contribute to the development of asbestosis.

Furthermore, Schwann cell detachment from axons may constitute an important early event for Schwann cell-derived tumours observed in NF2 (Miller et al., 2003).