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These genes may constitute conserved upstream regulators of the transcriptional response.
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Clusters 1-8 conservede conserved miRNAs, whereas clusters 9-12 conservedconserved and silkworm-specific miRNAs.
Thus, the Hsp70 subfamilies constitute conserved units of function and evolution.
Slits, netrins, semaphorins and the ephrins constitute conserved families of axonal guidance cues that have prominent developmental effects.
They showed that functionally related genes are frequently co-expressed across organisms constituting conserved transcription modules.
These observations suggest that integrin signaling may constitute a novel, conserved longevity pathway, yet the molecular underpinnings remain unknown.
The phylogenetic analysis indicates that these conserved orthologs may constitute a monophyletic lineage, albeit without high branch support.
This mechanism may be conserved in many organisms.
Furthermore, these 12 proteins may constitute a minimal set of evolutionarily conserved RBPs required for dendrite development across animal phyla.
Conserved motifs that may constitute the polyadenylation signal in a 50-bp region upstream and downstream of the mapped polyadenylation sites were searched using the qPMS7 algorithm for de novo motif search (Dinh et al. 2012; http://motifsearch.com/, last accessed July 15 , 2014.
We identified eight genes induced under CF conditions that were also conserved in the Bcc and may constitute particularly attractive therapeutic targets due to their signal sequence, predicted cellular location, and homology to known therapeutic targets.
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