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Hence, prior to application, the design may consider design itself if there is possibility of surface deterioration with course of time.
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Future research may consider better design and more representative sample for studying these issues.
In these situations, a clinical investigator may consider a design and analysis based on observational data (Table 1).
Where possible, researchers may want to consider designing studies which measure complications and compare determinants of preventive care-seeking with emergency care-seeking for complications.
Hence, we may consider the hybrid design.
Future trials may consider using pragmatic design adopting not only subjective patient-reported outcome measures but also objective outcome measures such as medication or other health service use [ 52].
Authors of submitted manuscripts using an observational study design may consider incorporating our scoring system or an equivalent in their methods and in reporting of the results.
One may consider a similar study design for controlled exposure in which the susceptible subjects are exposed to ambient levels of PM (with or without gaseous co-pollutants) and filtered air and assess the improvement in the biological endpoints.
Future studies may consider using alternative designs such as focus groups or individual interviews conducted by someone independent of the research project.
Future study designs may consider whether evening snacks may be omitted during closed-loop basal insulin delivery given that the risk of nocturnal hypoglycemia is mitigated through insulin-responsive insulin delivery.
Given that diabetes is primarily a self-managed disease, future studies may consider using metrics in study design and data analyses that allow assessing the actual impact of behavior-based interventions.
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