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However, abnormalities in specific brain structures and their interconnections may confer vulnerability to the development of late-life depression.
Preliminary findings suggest that anxiety sensitivity (AS) and intolerance of uncertainty (IU) may confer vulnerability for cyberchondria, defined as repeated internet searches for medical information that exacerbates health anxiety.
These findings outline a novel dopamine-dependent mechanism for perceptual modulation in physiological conditions and further suggest that this mechanism may confer vulnerability to hallucinations in hyper-dopaminergic states underlying psychosis.
Earlier neuroimaging studies revealed no cortical thinning [59] but anterior hippocampal deformity [60] in unaffected schizophrenic siblings, suggesting the hippocampal anatomy may confer vulnerability to the illness.
Some hypothesize the early onset of GAD may confer vulnerability to later-developing disorders, including depression [ 6].
If DNA repair capacity is limited in gametes, then selected life history traits such as long and synchronous periods of gametogenesis may confer vulnerability to genotoxic substances in chronic exposures.
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Behavioral studies in humans, rats and mice suggest that in utero alcohol exposure may confer increased vulnerability to substance misuse (including alcohol misuse) or addiction in young offspring and adolescents, which sometimes persists into adulthood [ 85- 90].
However, we cannot rule out that a trisomy may confer a vulnerability of the cells to subsequent malignant changes under appropriate stress conditions.
Fourth, research should not only examine the relationship between minority communities and exposures, but also study how the structural conditions of communities may confer additional vulnerability.
Reduced MeCP2 expression in brain has been observed in 79% of autism cortex samples (16) and functional variants of the MECP2 gene may confer autism vulnerability (17).
The significant interaction between depression and IL-17 concentrations predicting MMSE scores suggests that depression may confer neural vulnerability to IL-17 mediated inflammatory pathways.
More suggestions(15)
may reflect vulnerability
may indicate vulnerability
may underlie vulnerability
may heighten vulnerability
may influence vulnerability
may affect vulnerability
may promote vulnerability
may cause vulnerability
may exhibit vulnerability
may share vulnerability
may confer health
may confer disease
may consider vulnerability
may produce vulnerability
may increase vulnerability
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