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Shorter (GT n repeats in the HO-1 gene promoter may confer protective effects against cardiovascular mortality related to arsenic exposure.
A. fumigatus-specific CD4+ [17], [18], [18] and CD8+ T cells [17] have also been isolated from healthy patients, suggesting that routine exposure to A. fumigatus may confer protective immunity.
However, in some cases genetic polymorphisms may confer protective effects, such as those demonstrated for certain GSTP1 variants.
Whereas antioxidant enzymes may be preventive against cancer development, in already transformed cells, these enzymes may confer protective advantage of cancer cells in the hostile tumor microenvironment [ 40, 41].
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For intensively fed lambs, liver Cu accumulation and risk from Cu toxicity may be reduced, without loss of performance, by housing lambs on straw bedding when Mo is added to the diet and it is also possible that the Zn coating, frequently applied to protect metal flooring, may also confer protective properties evidenced in the absence of Mo.
These findings open up the exciting possibility that, as with the P. berghei Δp36p sporozoites, P. falciparum mutants lacking this gene may also confer protective immunity in humans against wild-type sporozoite infection.
For these types of infection, prior immunity caused by exposure to, or vaccination against, predecessor strains may not confer protective functional activity against newly emerged strains of the same pathogen [ 2, 4, 5].
While we did not demonstrate an association between dehiscence and technique of colpotomy, obesity may confer a protective effect through the physiologic property of increasing impedance in the monopolar circuit.
The manner by which HSV-2 co-infection may confer a protective effect on CD4+ T cell populations is not clear.
It is possible, for example, that changes in the quantity and distribution of adipose tissue in older age are adaptive and may confer a protective effect to the brain that minimizes the risk of cognitive decline, and that the loss of adipose tissue may deprive the aging brain of that benefit [31].
We showed that (i) mild hypothermia reduced myocardial damage and dysfunction after CPR and myocardial ischemia most probably due to attenuation of immune cell infiltration, apoptosis and pro-inflammatory cytokine expression, and (ii) pharmacological postconditioning with sevoflurane may confer additional protective effects on myocardium.
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