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The 6 less well-studied influenza virus gene segments may confer major determinants of infectivity, pathogenicity, transmissibility, and host species susceptibility (e.g., the role of the basic polymerase 2 gene segment in host range and virulence) (9 ).
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Because in parallel with a role in growth these signalling pathways also appear able to promote invasiveness of endocrine resistant cells, including UMB-1Ca [ 8, 12], such knowledge may reveal strategies that ultimately confer major improvements in patient prognosis.
Thus, traits which are expensive in terms of energy or time may be traded-off against other traits which do not confer major competitive advantages.
This is a major structural distortion that may confer resistance to nerve agent model compounds and disrupt enzymatic function of the enzyme itself.
Based on these results, we conclude from this study that specific phytocompound mixtures present as major or active components in the test traditional herb may confer defined and significant immuno-modulatory effects on specific immune cell types.
Certain major histocompatibility complex (MHC) class I and II alleles that may confer susceptibility to CLE include HLA B8, DR3, DQA1, and DRB1.
The existence of such major trans-acting regulatory QTL therefore suggests that alleles at these loci may confer some selective benefit to mitigate the deleterious effects on gene expression.
If the SA-related defense response is a major factor in soybean resistance to SCN, then components regulated by SA may confer resistance to SCN when overexpressed.
Instead, DISC1 disruption may confer a genetic risk at the level of endophenotypes or brain circuitry that underlies a number of major mental disorders.
Although we studied a major EGFR phosphorylation site, it is possible that activation at other EGFR autophosphorylation sites may confer prognostic information.
Given that Drotrecogin alfa has been shown to reduce the risk of death by 6% and that neuroaxial anaesthesia confers little survival benefit following major abdominal surgery, avoiding the use of or early removal of catheters in sepsis may confer a significant increase in survival.
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