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It is hypothesized that this region may confer differential properties of DOCK family function.
The native WT1 ±KTS) isoforms do not regulate any of these transcripts, indicating that the loss of zinc finger 1 and/or the presence of EWS transactivation domain (NTD) may confer differential target gene specificity to EWS/WT1.
Thus, we hypothesized that ABCB1 and ABCC10 may confer differential resistance to paclitaxel and cabazitaxel.
This suggests that subtle differences in the sequence/structure of chromodomains may confer differential affinity to different histone methylation patterns, for example, H3K9Me3 and H3K27Me3.
It has been reported that the overexpression of liver HSP70, particularly during the summer, may confer differential effects on cell survival by protecting against changes induced by oxidative stress [ 32].
It has also been hypothesised that variations in isoform expression may confer differential advantages on tumours as they expand in the different sites, each of which may possess different requirements for neovascularisation (Grunstein et al, 2000).
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Bio-X affiliates Tom Südhof and Marius Wernig have established a connection that may help explain why different genes confer differential Alzheimer's susceptibilities.
Our results support that, in addition to the classical drug resistance pathways, other major gene networks may interact by various mechanisms to confer differential response to chemotherapy.
Bresler, S. C. et al. ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma.
Some duplicate aaRS in bacteria confer differential antibiotic resistance against natural competitors [ 63].
Gender is one major variable that appears to confer differential vulnerability to stress.
More suggestions(15)
may destabilize differential
may confer tolerogenic
may require differential
may confer dominant-negative
may help differential
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may underlie differential
may confer invasive
may exert differential
may confer substantial
may confer cognitive
may imply differential
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