Sentence examples for may compromise cellular from inspiring English sources

During hypoxemia, the low tissue oxygen (O2) supply may compromise cellular aerobic metabolism and determine organ dysfunction.

PARP activity is involved in DNA damage repair and hence often seen as a benign factor, although excessive PARP activity may compromise cellular viability.

While the cellular targets are unknown, it is possible that cleavage of the N-terminal ubiquitin protease domain may compromise key cellular pathways normally regulated by Ataxin-3.

However, in some cases, PMs may be detrimental to protein functionality and may compromise the cellular functions in which they reside [ 45].

As a consequence, both loss of nuclear function(s) and gain of toxic function(s) in the cytoplasm may compromise various cellular processes in affected neurons, primarily RNA processing (7– 10), axonal transport (11) and neural transmission (12).

It is also worth noting that although the effective dose of an inhibitor may be specified by commercial vendors or literature, a pilot study should be conducted to optimize the concentration of an inhibitor for a specific cell line since too high concentration of an inhibitor may be toxic to cells and compromise cellular processes.

Similarly the function of "ER stress" is shared across two processes ("Cellular compromise", "Cellular function and maintenance").

In other cases, oxidation of protein residues that are structurally or functionally crucial may compromise protein functions, leading to cellular damage [26].

Neurodegeneration in the absence of plaque formation [4] [7] suggests that other presenilin-induced toxic cellular processes may compromise neuronal function independent of Aβ generation and ultimately set the stage for the onset of AD pathogenesis.

Promoting the co-localization of LKB1 and AMPK at the plasma membrane may compromise only one of the several cellular mechanisms that bring these enzymes together.

These alterations are linked to cellular migration and, importantly, may compromise the integrity of the gastric barrier [ 22- 26].