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Hypoxemia may compromise cell metabolism and organ function.
In this way, the cells remain protected from the accumulation of intracellular components that may compromise cell viability (2).
ER is responsible for an adequate protein synthesis, folding, and secretion and its disruption may compromise cell viability.
As represented in Fig. 4, our phosphoproteomic findings suggest a generalized dysregulation of the cytoskeleton signaling, which may compromise cell morphology and synaptic transmission.
Since molecular changes at the gene level may compromise cell function, it is important to understand the cellular response to reduced gravity at the molecular level.
In other cell types, however, decreased ATP concentration may compromise cell metabolism [ 51]; therefore, cells somehow sense the cytoplasmic ATP concentration as a signal to change gene expression to quickly readjust the mitochondrial architecture and cell metabolism [ 18, 52].
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This raises doubt whether NA may compromise cell-mediated immunity.
Results of this study show that perturbations in microenvironmental factors result in anatomical and gene expression change within the intervertebral disc that may ultimately compromise cell function and induce pathological deficits.
On the other hand, elevated SCCA may compromise the cell's ability to degrade misfolded proteins, and render tumor cells more vulnerable to treatment that causes proteotoxicity.
It appears that a complete loss of mitochondrial respiration may compromise the cell's ability to survive and proliferate in the in vivo tissue environment.
From the evolutionary analysis of repeats, the authors conclude that streptococcal repeats are largely parasitic and may compromise the cell's ability to compete in its environment; thus, surviving species have fewer mobile elements.
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