Age-related defects in the HSC compartment may also compound difficulties associated with allogeneic hematopoietic cell transplantation for the treatment of malignant and nonmalignant hematopoietic diseases, as prolonged periods of T-cell deficiency increase the risk of life-threatening complications (Mackall et al., 1995; Krenger et al., 2011).
Adjunctive therapies, like intermittent pneumatic compression, have proven benefit [ 29], but may compound patient difficulty with compliance, since, of necessity, these adjunctive treatment measures lengthen the daily requirement for self-management.
Although face recognition deficits in people with AD have traditionally been associated with memory impairments, our results suggest that an underlying problem with mental rotation may compound these recognition difficulties.
1 2 3 4 5 Persistent language delay is associated with poorer school and academic performance, more limited employment opportunities, and difficulties with social interactions and relationships. 2 3 Higher rates of behavioural problems may compound poorer educational, social, and employment outcomes.
Many have limited access to seed funds and microcredit, compounding difficulties in ending intergenerational poverty.
Most corn is used as animal feed.Higher corn prices may also compound the difficulties of companies that use corn to produce ethanol as a motor fuel.
Risk associated with depressive symptomatology in caregivers (parents and guardians) may further compound these difficulties.
Finally, the circadian rhythm abnormalities these patients exhibit may further compound their difficulties in subjectively assessing their own nocturnal sleep.
Although our results highlight the challenge of recognizing SARS among hospitalized patients, the occurrence of seasonal respiratory infections such as influenza may further compound the difficulty in identifying a SARS case.
