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These manufacturing changes may lead to micro-variants within the drug profile, which may have no clinical effect or may completely shift the immunogenicity profile, with changes in immune reaction potentially leading to altered efficacy and safety [ 2,36,37].
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Populations may also adapt genetically to new environmental conditions when there is no pre-existing adaptive phenotypic plasticity or plasticity is insufficient to completely shift a population to a new phenotypic optimum.
Now it has completely shifted with mobile and social converging.
The shifts in the processes and approach of the audit team completely shifted this footing.
This match has completely shifted around from the first half.
This completely shifts the power in the distribution system.
So, my feelings completely shifted.
Smith isn't completely shifting into monogamy.
When this happens your practice completely shifts.
"It completely shifts the burden of proof," he said.
Accordingly, dexamethasone completely shifted the impact of BaP on neurodifferentiation.
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