In particular, we explored the combination of D and hormonal therapy with the objective of targeting both the androgen-dependent and -independent cell subpopulations that may coexist at the primary tumour and/or micrometastatic disease.
Importantly, RAS and RUNX1 alterations are not exclusive, showing that, already, two oncogenic hits may coexist at this chronic stage.
Surprise, unexpectedness and admiration may coexist, so that it is difficult to clearly separate them.
Nevertheless, the conflicting nature of published reports on the conformational bias in monomeric Aβ suggests several aggregation-prone conformations may coexist and that environment heavily influences the route taken by most of these molecules.
Phase systems are governed by a phase rule, which defines the number of minerals that may coexist in equilibrium: F = C - P + 2, where F is the variance, or number of degrees of freedom, C is the number of independent components, and P is the number of phases.
Key findings for the diagnosis of sarcoidosis are the more typical findings of sarcoidosis that may coexist as ancillary findings, i.e. the micronodules along all aspects of interstitium, the beading of the fissures and the lymphadenopathy.
Significantly, the Tb-AIP MMMs show highly selective and sensitive to nitrofuran antibiotics (NFAs) via inner filter effect (IFE), and yet remain unaffected not only by other common antibiotics but also by other types of analytes (metal ions and anions) that may coexist.
These studies show that the spike-adding mechanism is formed by a pair of saddle-node bifurcations of periodic orbits of the full system; bursts with different numbers of spikes are, in fact, different periodic attractors of the full system that may coexist only if the number of spikes differs by one [20, 26].
In vivo, there are many endogenous inducers of ER stress, e.g., unesterified cholesterol from host-derived lipoproteins, oxysterols, and peroxynitrite that may coexist with various SRA, TLR4, CD36, and TLR2 ligands in granulomas, e.g., mycobacteria and their lipid products and oxidized-phospholipids [30], [31], [47] [49].
This case illustrates the complexity of renal lesions that may coexist.
