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On the other hand, doctors know that chronic use may change serum electrolytic concentrations.
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The high prevalence of underlying co-morbidities in TB patients may change the serum levels of biomarkers and lead to a relatively high mortality rate.
It is suggested that dietary fats may change the serum PON1 activity via affecting the synthesis and secretion of phospholipids and apo-A-I within very high density lipoprotein (VHDL), the main transporter of PON1 and LCAT molecules in blood [ 14].
Chemotherapy treatment may change GPS and serum tumor markers level, and the change of GPS and serum tumor markers level may be related with chemotherapy response.
Despite the knowledge that individual serum batches differ in their composition and may change properties over time, serum is still commonly used in immunologic assays.
Most serum GGT is bound to lipoproteins, more dominantly to Apo A than to Apo B, although the ratio may change depending on the serum lipid profile [ 6, 8- 11, 41].
Of importance, several studies in patients with inflammatory arthritis have shown that some of these markers of bone and cartilage metabolism are associated with progression of radiographic joint damage [13] [15], and that their tissue expression and serum levels may change after initiation of effective (biologic) therapy [13], [16] [19].
Serum BDNF levels may change only with successful medication [ 19], and our patients were not responsive to the medications they were receiving at the time of the study.
That may change, however.
Unfortunately, that may change.
But things may change.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com