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However, increasing the boron levels in body liquids may cause toxicity.
Traditionally O2 is considered as a drug that may cause toxicity and current guidelines recommend using the lowest FiO2 possible.
Nitrate accumulation in closed systems where water changes are expensive and problematic may cause toxicity problems to marine life.
Increase of concentration of trace elements in soils due to prolonged application of composts may cause toxicity to plants, animals and humans.
Despite being a "regional" anticoagulation technique, a major fraction of the infused citrate reaches the patient systemic circulation and may cause toxicity.
Various assays with adult fish have been developed to identify potential endocrine-disrupting chemicals (EDCs) which may cause toxicity via alterations in the hypothalamic pituitary gonadal (HPG) axis.
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Certain metals, including copper, may inhibit root growth, most likely by inhibiting cell division, and may also cause toxicity and cytotoxicity [ 51].
However, L-asparaginase may also cause toxicity without inducing programmed cell death [46] [49].
Generation of ROS and RNS may, hypothetically, cause toxicity in bacteria as well.
In some cases, bioavailability enhancement through micellar solubilization and emulsification may also cause toxicity to the microorganisms and hinder the biodegradation of petroleum hydrocarbons.
Background: Nucleoside reverse transcriptase inhibitors (NRTIs) used in antiretroviral therapy may cause mitochondrial toxicity.
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