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In particular, the wMelPop strain is a virulent strain that may cause tissue damage and sickness.
Decalcification of osseous specimens is required for histological analysis; this however may cause tissue damage.
The newer metal-on-metal hip implants, for instance, are somewhat controversial and may cause tissue and bone damage in certain patients.
However, while chitosan can disrupt the cell membrane integrity and may induce blood thrombosis, PLGA releases acidic byproducts that may cause tissue inflammation and interfere with the healing process.
Severe infection or trauma induces inflammation, leading to: (i) the recruitment of neutrophils to the site of infection; (ii) misdirected neutrophil recruitment to healthy tissue, which may cause tissue damage; and (iii) an increase in neutrophil production through the G-CSF signaling cascade.
However, long-term usage and limb swelling may cause tissue herniation into the lattice structure.
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Further analyses of other mutant forms of TTR will provide additional insights into distinct misfolding pathways of TTR variants that may cause tissue-selective TTR amyloidosis.
This methylation may cause tissue-specific expression of genes between embryo and endosperm.
Accordingly, defects in ubiquitous calpains can be lethal, as seen in Capn2 −/− and Capns1 −/− mice, whereas defects in tissue-specific calpains may cause tissue-specific phenotypes, such as the muscular dystrophy caused by CAPN3 mutations.
The developmental mitotic origin of most CNVs that may lead to MZ twin discordance may also cause tissue differences within individuals during a single pregnancy and generate a high frequency of mosaics in the population.
Tissue reperfusion following hemorrhagic shock may paradoxically cause tissue injury and organ dysfunction by mitochondrial free radical expression.
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