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The present study indicates that colchicine induced neuroinflammation may cause systemic inflammation and alteration of immune responses which are mediated by increased cox- 2 activity.
This is of grave importance in order to prevent septicemia, as very few bacteria in circulation may cause systemic infection leading to death.
The condition may cause systemic inflammation, which may potentially damage multiple organs in the body, including the heart [ 5].
Our data indicate that cycloviruses may cause systemic infections and are present in multiple organ compartments in humans.
Toxoplasma gondii and Toxocara spp. infections are cosmopolitan zoonotic diseases which may cause systemic and ocular diseases in humans [ 7- 9].
Corrosion of titanium ions in the surrounding tissue and the movement of these ions into the distant organs may cause systemic problems.
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Brimonidine may occasionally cause systemic side effects, such as blood pressure changes or neurological symptoms and may cause ocular intolerance in approximately 10%-26 10%-26ses [ 57, 58].
Psychological stress may cause a systemic hypertension or valsalva maneuver which leads to an increase in systemic and orbital venous pressure during flights and to our knowledge this is the first case presented with intraorbital subperiostal haematoma during a commercial flight.
It may cause a systemic infection, involving the skin, joints, heart, nervous system, and sometimes the eye [3].
Cadmium is one of the most prevalent nephrotoxic heavy metal, but it may cause other systemic toxicity as well.
However, its biocompatibility has always been in controversy since the passive film developed on the surface can release metallic ions (Ni2+, Cr3+ and Cr6+), which may cause local systemic effects into the human body and therefore, the premature failure of implant as result of inflammatory reactions.
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may compromise systemic
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