Sentence examples for may cause steric from inspiring English sources

Notably, the first Gly is invariant among all TAL effectors because any other residue with a side group at this position may cause steric clash with the DNA backbone (Fig. 5A, central panel).

Although the kinase domain is not required for enhanced signaling, inhibition of its kinase activity may cause steric hindrance or prevent conformational changes of signaling complexes preventing downstream signaling events.

During the binding of TFO with the DNA double helix in the major groove, Au NPs and other TFOs may cause steric hindrance, but 2 nm Au NPs are even smaller than the width of the major groove (22 Å).

Lipase-catalyzed esterification of FFAs is likely to be more efficient than direct transesterification of triglycerides because three acyl groups tethered to the glycerol backbone may cause steric hindrance for enzyme access [ 21].

This affinity enhancement can be ascribed to the removal of the outer carbohydrate branches of the N-glycan at Asn-45, which are in close spatial proximity to the CH2 domain of Fc chain B and may cause steric hindrance, although their electron densities are not interpretable (Fig. 5A).

Substitution of valine with isoleucine in the α3β2 (V111I) nAChR subtype may cause a steric clash between Val-10 and β2 V-111, explaining the decreased binding affinity of LvIA.

Concentrations exceeding the optimal condition may cause the steric hindrance of the antibodies absorbed on the surface and consequently result in the decreased antibody antigen binding efficiency.

When Hunte and coworkers identified the lipid-binding motif, they noted that it did not seem to apply to PC lipids and suggested that this may be due to the large choline headgroup that could cause steric clashes (Palsdottir and Hunte, 2004).

The immobilization of enzymes onto the cell wall may block the movement of processive enzymes (e.g., CBHI) or cause steric restriction in the collision with cellulose.

On the other hand, an antibody directed against the EC2 domain, although this part of the molecule may not be involved in transinteraction, might be large enough to cause steric hindrance of Dsg 3 transinteraction.

In addition, the GFP tag could cause steric hindrance and thereby interfere with the interaction between XHSBP1 and HSF1.