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However, the chitosan coating may cause resistance in external mass transfer.
In cholangiocarcinoma cells, activation of PI3K/AKT may cause resistance to oxaliplatin-induced cytotoxicity (Hayward et al., 2004).
In conclusion, we believe our findings here that mutations in the TP53 and CHEK2 genes each may cause resistance to anthracycline therapy in primary tumors to have wide implications to future research in this area.
Yet, based on the finding that the Arg117Gly mutant expressed no intrinsic activity, but readily dimerized to the wild-type protein without abolishing its activity, we hypothesize that this mutation and, probably, other yet unidentified CHEK2 mutations with a similar lack of intrinsic kinase activity, may cause resistance to anthracycline therapy if combined with LOH in breast cancer.
Conversely, persistent oxidative stress at sublethal levels may cause resistance to apoptosis.
Nevertheless, long-term therapy with NUCs may cause resistance or virological breakthrough.
Similar(37)
The fact that none of the Arg175His patients presented here or in our previous study revealed resistance to therapy (PD) suggests this mutation may not cause resistance to anthracyclines in breast cancers in vivo.
Persistent oxidative stress within carcinoma cells may therefore cause resistance to therapy.
And high intakes of trans fats may cause insulin resistance, a marker of type 2 diabetes.
Talking about it may cause some resistance – and some eye rolling.
The electroforming process usually requires a higher bias and may cause unstable resistance states [8], which make RS characteristics very difficult to modulate.
More suggestions(15)
may heighten resistance
may be resistance
may cause damage
may cause power
may encourage resistance
may regulate resistance
may exhibit resistance
may perform resistance
may cause memory
may improve resistance
may exacerbate resistance
may show resistance
may reduce resistance
may evolve resistance
may promote resistance
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